To meet many of today’s most pressing challenges, we need to find new solutions. But the fastest, cheapest, and most effective way to encourage high-impact innovation isn’t always obvious. Governments, philanthropists, and the private sector typically invest in research and development (R&D) by bett...

The experience of the COVID-19 pandemic—in the US and around the world—highlights the potential feasibility and importance of biomedical R&D for global health and welfare. Drawing from this experience and momentum, this paper argues that the US should deepen its engagement and ambition in global hea...

Pull financing is an underutilized tool that can drive the development and adoption of critical technologies necessary to address the globe’s climate crisis. This paper provides tangible examples by presenting two case studies that illustrate how pull climate finance can be used to deliver urgently ...

Pull financing is a powerful but underused mechanism for incentivising progress on hard-to-tackle social problems for which innovation or the take-up of innovation may be part of the solution. It should become part of the ongoing landscape for climate and development work. This paper sets out the sp...

The COVID-19 pandemic has transformed the global vaccine manufacturing landscape, with capacity more than doubling in the past 18 months. Before the pandemic, manufacturers produced an estimated total of five billion vaccine doses each year. In 2021, manufacturers produced 12 billion doses of C...