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Priority-setting in health is a critical function of all health systems, enabling countries to focus their spending on services that have the biggest impact on their citizens’ health. This works—for every dollar spent on priority-setting, countries get nine dollars of better health system impact. Ho...

The passing of the Inflation Reduction Act (IRA) could result in nearly $100 billion in savings over a decade, but opponents of value assessment have voiced their concerns. The alternative? External Reference Pricing (ERP).

So is adaptive HTA, which is a “second-best” approach to locally informed and conducted HTA even in the best of circumstances, the only option available for MICs without a fully-funded process? We think there’s another possibility—virtual HTA.

Though there are various definitions of HTA, and different approaches for considering evidence on clinical effectiveness, economics, social values, and ethics, there is a universal emphasis on generating transparent and evidence-informed recommendations for health coverage decisions. ...

Despite their intended use for rare diseases, so-called orphan drugs contribute substantially to prescription drug spending; in fact, it is estimated that in just two years’ time, orphan drugs will constitute more than 20 percent of the market for global pharmaceutical sales. Nowhere is t...