Each of the cases in Millions Saved adheres to five selection criteria:
- Scale: Interventions or programs that were implemented on a national, regional or global scale.
- Importance: Interventions that addressed a problem of health significance, measured by the burden of disease.
- Impact: Interventions or programs that demonstrated a clear and measurable impact on the health of a population.
- Duration: Interventions or programs that functioned "at scale" for at least five consecutive years.
- Cost-effectiveness: Interventions or programs that used a cost-effective approach, using a threshold of about US $100 per disability-adjusted life-year saved.
